Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7652933 | 0.76 | MEN1 (0.41) | MEN1KMT2ATSHRMAPK1 | |
| Triethylene Glycol SCHEMBL15413179 | 0.76 | MEN1 (0.69) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL9556920 | 0.74 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL11145760 | 0.73 | TSHR (0.67) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL7654929 | 0.72 | MEN1 (0.44) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL28630734 | 0.71 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL6153065 | 0.71 | TSHR (0.62) | MEN1KMT2ATSHRMAPK1CXCR4 | |
| SCHEMBL27297736 | 0.69 | SLC29A1 (0.36) | MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL1276025 | 0.68 | KDM4E (0.48) | MEN1KMT2ATSHRMAPK1CXCR4 | |
| SCHEMBL10526359 | 0.68 | KDM4E (0.48) | MEN1KMT2ATSHRMAPK1CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487334-A4 | PARAMAGNETIC PARTICLES THAT PROVIDE IMPROVED RELAXIVITY | BARNES JEWISH HOSPITAL (US) | 2006-10-25 | — | — | EP | claimed |
| JP-2005521704-A | — | — | 2005-07-21 | — | — | JP | claimed |
| EP-1487334-A1 | PARAMAGNETIC PARTICLES THAT PROVIDE IMPROVED RELAXIVITY | Barnes-Jewish Hospital (US) | 2004-12-22 | — | — | EP | claimed |
| WO-2003082105-A1 | PARAMAGNETIC PARTICLES THAT PROVIDE IMPROVED RELAXIVITY | BARNES-JEWISH HOSPITAL (US) | 2003-10-09 | — | — | WO | claimed |