Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | POLA1 | P09884 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031247 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TDP1EHMT2KMT2AMEN1 | |
| SCHEMBL9031613 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1EHMT2KMT2AMEN1 | |
| SCHEMBL9032781 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1EHMT2KMT2AMEN1 | |
| SCHEMBL9030364 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1EHMT2KMT2AMEN1 | |
| SCHEMBL11199133 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1EHMT2KMT2AMEN1 | |
| SCHEMBL10721577 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1EHMT2KMT2AMEN1 | |
| SCHEMBL9030374 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1EHMT2KMT2AMEN1 | |
| SCHEMBL11177434 | 0.95 | ALDH1A1 (0.50) | ALDH1A1TDP1EHMT2KMT2AMEN1 | |
| SCHEMBL10915180 | 0.87 | ALDH1A1 (0.46) | ALDH1A1TDP1EHMT2KMT2AMEN1 | |
| SCHEMBL10375914 | 0.87 | ALDH1A1 (0.46) | ALDH1A1TDP1EHMT2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011160-A1 | 6,7-DIHYDRO-4H-PYRAZOLO[1,5-A]PYRAZINE COMPOUNDS FOR THE TREATMENT OF INFECTIOUS DISEASES | F. HOFFMANN-LA ROCHE AG (CH) | 2018-01-18 | — | — | WO | disclosed |
| JP-2006232743-A | METHOD FOR PRODUCING DIMETHYL-1, 3-DIBENZYL-2-OXO- IMIDAZOLIDINE-4, 5-DICARBOXYLATE | SUMITOMO CHEMICAL CO LTD | 2006-09-07 | — | — | JP | disclosed |
| EP-0084892-B2 | Preparation of optically active cis-1,3-dibenzyl-hexahydro-1H-furo(3,4-d)imidazole-2,4-dione and its intermediates | SUMITOMO CHEMICAL CO (JP) | 1996-10-23 | — | — | EP | disclosed |
| EP-0084892-B1 | PREPARATION OF OPTICALLY ACTIVE CIS-1,3-DIBENZYL-HEXAHYDRO-1H-FURO(3,4-D)IMIDAZOLE-2,4-DIONE AND ITS INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-12-23 | — | — | EP | disclosed |
| US-4544635-A | Preparation of optically active cis-1,3-dibenzyl-hexahydro-1H-furo[3,4-d]imidazole-2,4-dione and its intermediates | SUMITOMO CHEMICAL CO., LTD. (JP) | 1985-10-01 | — | — | US | disclosed |
| US-4496739-A | Intermediates to optically active cis-1,3-dibenzyl-hexahydro-1H-furo[3,4-d]imidazole-2,4-dione | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-01-29 | — | — | US | disclosed |
| EP-0084892-A2 | Preparation of optically active cis-1,3-dibenzyl-hexahydro-1H-furo(3,4-d)imidazole-2,4-dione and its intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-08-03 | — | — | EP | disclosed |