Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049377 | 0.85 | MAPT (0.41) | L3MBTL1KDM4EALDH1A1GAALMNA | |
| SCHEMBL6049335 | 0.82 | L3MBTL1 (0.39) | L3MBTL1KDM4EALDH1A1GAALMNA | |
| SCHEMBL2091560 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1GAAMAOB | |
| SCHEMBL9721587 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1GAAMAOB | |
| SCHEMBL31096458 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1GAAMAOB | |
| SCHEMBL6573378 | 0.79 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1GAAMAOB | |
| SCHEMBL8811646 | 0.79 | KDM4E (0.60) | L3MBTL1KDM4EALDH1A1GAAMAOB | |
| SCHEMBL6049333 | 0.78 | CETP (0.38) | L3MBTL1PTGESALOX5PPARGPPARA | |
| SCHEMBL2089594 | 0.78 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1GAAMAOB | |
| SCHEMBL7199882 | 0.78 | L3MBTL1 (0.57) | L3MBTL1KDM4EALDH1A1GAAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539136-A4 | PPAR ALPHA SELECTIVE COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER LIPID DISORDERS | MERCK & CO INC (US) | 2006-10-18 | — | — | EP | disclosed |
| EP-1539136-A2 | PPAR ALPHA SELECTIVE COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER LIPID DISORDERS | Merck & Co., Inc. (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004010936-A2 | PPAR ALPHA SELECTIVE COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER LIPID DISORDERS | MERCK & CO., INC. (US) | 2004-02-05 | — | — | WO | disclosed |