Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 3/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | BMP1 | P13497 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049343 | 1.00 | BACE1 (0.48) | BACE1PTPN1CTSDEGFRGLO1 | |
| SCHEMBL31676630 | 0.94 | BACE1 (0.44) | BACE1PTPN1CTSDEGFR | |
| SCHEMBL30555686 | 0.90 | DPP4 (0.45) | BACE1CTSDGLO1 | |
| SCHEMBL29814935 | 0.89 | GLO1 (0.43) | BACE1CTSDGLO1BMP1BACE2 | |
| SCHEMBL30963041 | 0.89 | BACE1 (0.58) | BACE1CTSD | |
| SCHEMBL31676654 | 0.88 | FOLH1 (0.46) | BACE1CTSDEGFRGLO1 | |
| SCHEMBL31676656 | 0.88 | FOLH1 (0.46) | BACE1CTSDEGFRGLO1 | |
| SCHEMBL31676622 | 0.88 | FOLH1 (0.46) | BACE1CTSDEGFRGLO1 | |
| SCHEMBL29431016 | 0.88 | PTGS1 (0.44) | BACE1CTSDGLO1BMP1 | |
| SCHEMBL30563243 | 0.88 | DPP4 (0.45) | BACE1CTSDGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100457908-C | Recombinant stratum corneum chymotrypsin (SCCE) | AGRU T (SE) | 2009-02-04 | — | — | CN | disclosed |
| EP-1398326-B1 | Monoclonal antibodies against recombinant stratum corneum chymotryptic enzyme (SCCE) | THORBJOERN EGELRUD (SE) | 2006-01-11 | — | — | EP | disclosed |
| EP-1398326-A2 | Monoclonal antibodies against recombinant stratum corneum chymotryptic enzyme (SCCE) | Egelrud, Torbjörn (SE) | 2004-03-17 | — | — | EP | disclosed |
| EP-0703985-B1 | RECOMBINANT STRATUM CORNEUM CHYMOTRYPTIC ENZYME (SCCE) | EGELRUD TORBJOERN (SE) | 2003-10-29 | — | — | EP | disclosed |
| US-5981256-A | NUCLEOTIDE SEQUENCE CODING A PROTEOLYTIC POLYPEPTIDE FOR THE TREATMENT OR PROPHYLAXIS OF DISEASES SUCH AS ACNE, PSORIASIS, ECZEMAS, SKIN DISORDERS, AUTOIMMUNE AND INFLAMMATORY SKIN DISEASES | ASTRA AKTIEBOLAG (SE) | 1999-11-09 | — | — | US | disclosed |
| US-5834290-A | SKIN DISORDERS SUCH AS ACNE, XERODERMA, HYPERKERATOTIC CONDITIONS, CALLOSITIES AND KERATOSIS PILARIS; ICHTHYOSES, PSORIASIS AND ECZEMAS; AUTOIMMUNE PEMPHIGUS, ACATHOLYTIC DISEASES, FAMILIAR PEMPHIGUS AND DARIER'S DISEASE | ASTRA AKTIEBOLAG (SE) | 1998-11-10 | — | — | US | disclosed |
| CN-1128047-A | Recombinant stratum corneum chymotryptic enzyme (SCCE) | SYMBICOM AB (SE) | 1996-07-31 | — | — | CN | disclosed |
| EP-0703985-A1 | RECOMBINANT STRATUM CORNEUM CHYMOTRYPTIC ENZYME (SCCE) | Astra Aktiebolag (SE) | 1996-04-03 | — | — | EP | disclosed |
| WO-1995000651-A1 | RECOMBINANT STRATUM CORNEUM CHYMOTRYPTIC ENZYME (SCCE) | ASTRA AKTIEBOLAG (SE) | 1995-01-05 | — | — | WO | disclosed |