SCHEMBL6049348

SCHEMBL6049348

CCCCSc1ccc([N+](=O)[O-])c2nonc12

nearest known ligand 0.74

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 19/20 0.74
GSTM2 P28161 19/20 0.74
IDO1 P14902 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6049336 0.85 GSTP1 (1.00) GSTP1GSTM2
SCHEMBL761344 0.84 GSTP1 (1.00) GSTP1GSTM2
SCHEMBL6056044 0.84 GSTP1 (1.00) GSTP1GSTM2
SCHEMBL300204 0.83 GSTP1 (0.82) GSTP1GSTM2
SCHEMBL13906505 0.82 GSTP1 (0.76) GSTP1GSTM2IDO1
SCHEMBL27142039 0.81 GSTP1 (0.77) GSTP1GSTM2
SCHEMBL3502370 0.80 GSTP1 (0.74) GSTP1GSTM2
SCHEMBL3502174 0.78 GSTP1 (0.72) GSTP1GSTM2IDO1
SCHEMBL18878890 0.78 GSTP1 (0.77) GSTP1GSTM2IDO1
SCHEMBL13997681 0.77 GSTP1 (0.66) GSTP1GSTM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1615638-B1 USE OF 7-NITRO-2,1,3 BENZOXADIAZOLE DERIVATIVES FOR ANTICANCER THERAPY UNIV ROMA (IT) 2006-09-27 EP disclosed