Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTP1 | P09211 | 15/20 | 0.72 |
| ▸ | GSTM2 | P28161 | 15/20 | 0.72 |
| ▸ | IDO1 | P14902 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18878890 | 0.86 | GSTP1 (0.77) | GSTP1GSTM2IDO1KDM4EMEN1 | |
| SCHEMBL7052057 | 0.84 | GSTM2 (0.66) | GSTP1GSTM2IDO1MEN1ALDH1A1 | |
| SCHEMBL297920 | 0.79 | IDO1 (1.00) | GSTP1GSTM2IDO1CASP6 | |
| SCHEMBL2608494 | 0.79 | GSTP1 (0.61) | GSTP1GSTM2IDO1MEN1POLB | |
| SCHEMBL6836307 | 0.78 | GSTP1 (1.00) | GSTP1GSTM2IDO1KDM4EMEN1 | |
| SCHEMBL6049348 | 0.78 | GSTP1 (0.74) | GSTP1GSTM2IDO1 | |
| SCHEMBL300204 | 0.77 | GSTP1 (0.82) | GSTP1GSTM2 | |
| SCHEMBL6833698 | 0.77 | IDO1 (0.78) | GSTP1GSTM2IDO1KDM4EMEN1 | |
| SCHEMBL18896958 | 0.77 | IDO1 (0.76) | GSTP1GSTM2IDO1KDM4EMEN1 | |
| SCHEMBL6049433 | 0.76 | IDO1 (0.76) | GSTP1GSTM2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | claimed |
| EP-2190290-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | University Of Durham (GB) | 2010-06-02 | — | — | EP | claimed |
| WO-2009034396-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | UNIVERSITY OF DURHAM (GB) | 2009-03-19 | — | — | WO | claimed |
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | disclosed |
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | disclosed |
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | UNIVERSITY OF DURHAM (GB) | 2010-07-22 | — | — | US | disclosed |
| EP-2190290-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | University Of Durham (GB) | 2010-06-02 | — | — | EP | disclosed |
| WO-2009034396-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | UNIVERSITY OF DURHAM (GB) | 2009-03-19 | — | — | WO | disclosed |
| WO-2009034396-A2 | METHOD AND MEANS RELATING TO MULTIPLE HERBICIDE RESISTANCE IN PLANTS | UNIVERSITY OF DURHAM (GB) | 2009-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184601-A1 | Method and Means Relating to Multiple Herbicide Resistance in Plants | GSTO1, GSTP1, GSR | GSTP1 2/4885GSTM2 5/4885IDO1 3045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.