SCHEMBL6049397

SCHEMBL6049397

CCN(C)S(=O)(=O)NC(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 17/20 0.34
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
CYP2C19 P33261 1/20 0.32
BRAF P15056 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6049420 0.93 SCN9A (0.33) SCN9APOLBAPEX1CYP2C19
SCHEMBL30930656 0.92 POLB (0.34) SCN9APOLBAPEX1
SCHEMBL7220420 0.92 POLB (0.34) SCN9APOLBAPEX1
SCHEMBL6049393 0.91 SCN9A (0.34) SCN9APOLBAPEX1
SCHEMBL4065246 0.91 SCN9A (0.42) SCN9A
SCHEMBL6049432 0.91 SCN9A (0.36) SCN9APOLBAPEX1
SCHEMBL6049356 0.90 SCN9A (0.34) SCN9APOLBAPEX1CYP2C19BRAF
Saflufenacil SCHEMBL712168 0.90 SCN9A (0.39) SCN9APOLBAPEX1
Saflufenacil SCHEMBL29349941 0.90 SCN9A (0.39) SCN9APOLBAPEX1
SCHEMBL27559547 0.89 SCN9A (0.33) SCN9APOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1458237-B1 HERBICIDAL MIXTURE BASED ON 7-PYRAZOLYLBENZOXAZOLES BASF AG (DE) 2006-04-12 EP claimed
US-20050037923-A1 Herbicidal mixture based on 7-pyrazolybenzoxazoles BASF AKTIENGESELLSCHAFT (DE) 2005-02-17 US claimed
CN-1383425-A Uracil substituted phenyl sulfamoyl carboxamides BASF AG (DE) 2002-12-04 CN claimed
EP-1458237-B1 HERBICIDAL MIXTURE BASED ON 7-PYRAZOLYLBENZOXAZOLES BASF AG (DE) 2006-04-12 EP disclosed
US-20050037923-A1 Herbicidal mixture based on 7-pyrazolybenzoxazoles BASF AKTIENGESELLSCHAFT (DE) 2005-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050037923-A1 Herbicidal mixture based on 7-pyrazolybenzoxazoles DDT, CYP2W1, CYP3A7 SCN9A 3213/4885POLB 3186/4885APEX1 4663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.