Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18422247 | 0.91 | MEN1 (0.46) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL1451594 | 0.91 | MEN1 (0.46) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL3594946 | 0.91 | MEN1 (0.46) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL6050397 | 0.91 | MEN1 (0.46) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL677748 | 0.89 | CYP1A2 (0.44) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL677482 | 0.85 | CYP1A2 (0.50) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL1404339 | 0.80 | MCHR1 (0.39) | MEN1LMNACHRM2MAPTHTR2B | |
| SCHEMBL8166039 | 0.77 | CYP1A2 (0.45) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL15410684 | 0.75 | NR5A1 (0.40) | MEN1NR1I2LMNACHRM2CYP3A4 | |
| SCHEMBL11375442 | 0.75 | CYP1A2 (0.43) | MAPTMCHR1CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494658-B1 | NATURAL PHENOLIC PRODUCTS AND DERIVATIVES THEREOF FOR PROTECTION AGAINST NEURODEGENERATIVE DISEASES | PULEVA BIOTECH SA (ES) | 2006-01-04 | — | — | EP | claimed |