SCHEMBL6050581

SCHEMBL6050581

Clc1cc(NC2CCCCC2)nc(Cl)n1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.60
MEN1 O00255 2/20 0.60
NUDT1 P36639 1/20 0.49
CDC7 O00311 2/20 0.48
GSK3B P49841 2/20 0.48
CHEK1 O14757 1/20 0.48
MAPK13 O15264 1/20 0.48
PDPK1 O15530 1/20 0.48
DAPK3 O43293 1/20 0.48
DYRK3 O43781 1/20 0.48
PAK4 O96013 1/20 0.48
CHEK2 O96017 1/20 0.48
EGFR P00533 1/20 0.48
PRKCG P05129 1/20 0.48
CDK1 P06493 1/20 0.48
LYN P07948 1/20 0.48
ROS1 P08922 1/20 0.48
FER P16591 1/20 0.48
PRKACA P17612 1/20 0.48
RPS6KB1 P23443 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9084790 0.98 KMT2A (0.57) KMT2AMEN1NUDT1CDC7GSK3B
SCHEMBL9085696 0.96 KMT2A (0.56) KMT2AMEN1NUDT1CDC7GSK3B
SCHEMBL11659063 0.91 MEN1 (0.47) KMT2AMEN1NUDT1CDC7GSK3B
SCHEMBL6128335 0.83 KCNN2 (0.56) KMT2AMEN1NUDT1CDC7PDE4A
SCHEMBL1318447 0.83 NUDT1 (0.67) KMT2AMEN1NUDT1CDC7GSK3B
SCHEMBL16711168 0.83 NUDT1 (0.67) KMT2AMEN1NUDT1CDC7GSK3B
SCHEMBL12526926 0.83 HRH3 (0.45) KMT2AMEN1CDC7GSK3BCHEK1
SCHEMBL9083981 0.82 MEN1 (0.56) KMT2AMEN1NUDT1CDC7GSK3B
Hydrochloric Acid SCHEMBL1748357 0.81 HRH3 (0.44) KMT2AMEN1CDC7GSK3BCHEK1
SCHEMBL25166304 0.81 KCNN2 (0.54) KMT2AMEN1NUDT1CDC7PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1664135-A1 STABILIZATION OF METHYLMETHACRYLATE-BUTADIENE-STYRENE GRAFT COPOLYMERS AGAINST THERMAL OXIDATION Ciba SC Holding AG (CH) 2006-06-07 EP disclosed
EP-1539873-A2 STABILLIZATION OF ORGANIC MATERIALS Ciba SC Holding AG (CH) 2005-06-15 EP disclosed
WO-2005023886-A1 STABILIZATION OF METHYLMETHACRYLATE-BUTADIENE-STYRENE GRAFT COPOLYMERS AGAINST THERMAL OXIDATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-03-17 WO disclosed
WO-2004024810-A2 STABILLIZATION OF ORGANIC MATERIALS CIBA, SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-03-25 WO disclosed