Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15900454 | 0.73 | HPGD (0.37) | MAPTMEN1KMT2AHPGDTDP1 | |
| SCHEMBL3675404 | 0.73 | CA1 (0.51) | MAPTATMPOLBMEN1KMT2A | |
| SCHEMBL16670318 | 0.73 | POLB (0.55) | MAPTPOLBNPSR1MEN1KMT2A | |
| SCHEMBL11610539 | 0.72 | HPGD (0.36) | MAPTPOLBMEN1KMT2APKM | |
| SCHEMBL2585993 | 0.72 | HPGD (0.36) | MAPTMEN1KMT2AHPGDTDP1 | |
| SCHEMBL2593906 | 0.72 | MAPT (0.40) | MAPTATMTSHRMEN1KMT2A | |
| SCHEMBL16670248 | 0.70 | POLB (0.52) | MAPTPOLBNPSR1MEN1KMT2A | |
| SCHEMBL2589835 | 0.69 | HPRT1 (0.41) | MAPTTSHRHPGDTDP1ALDH1A1 | |
| SCHEMBL2593632 | 0.68 | HPGD (0.41) | MAPTPOLBMEN1KMT2APKM | |
| SCHEMBL3965834 | 0.67 | MAPT (0.36) | MAPTATMPOLBNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018134399-A1 | NOVEL PRODRUGS OF MIZORIBINE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-07-26 | — | — | WO | disclosed |
| EP-1636232-A2 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | 4 AZA Bioscience nv (BE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004104005-A2 | IMMUNOSUPPRESSIVE EFFECTS OF PTERIDINE DERIVATIVES | 4 AZA BIOSCIENCE NV (BE) | 2004-12-02 | — | — | WO | disclosed |