SCHEMBL2593906

SCHEMBL2593906

[c]1c(-c2cccc3ccccc23)ccc2oc3ccccc3c12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.40
HPGD P15428 6/20 0.40
KDM4E B2RXH2 6/20 0.40
ALDH1A1 P00352 5/20 0.40
HSD17B10 Q99714 5/20 0.40
GAA P10253 1/20 0.40
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MAOA P21397 2/20 0.38
MAOB P27338 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.36
GLA P06280 2/20 0.36
CYP3A4 P08684 1/20 0.36
PGAM1 P18669 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2589835 0.92 HPRT1 (0.41) MAPTHPGDKDM4EALDH1A1HSD17B10
SCHEMBL15900454 0.85 HPGD (0.37) MAPTHPGDKDM4EALDH1A1HSD17B10
SCHEMBL2585993 0.84 HPGD (0.36) MAPTHPGDKDM4EALDH1A1HSD17B10
SCHEMBL11610539 0.81 HPGD (0.36) MAPTHPGDKDM4EALDH1A1HSD17B10
SCHEMBL6566240 0.77 BCHE (0.40)
SCHEMBL2585053 0.77 PNMT (0.37) MAPTHPGDKDM4EALDH1A1HSD17B10
SCHEMBL3796974 0.76 MAOB (0.43) MAPTHPGDKDM4EALDH1A1HSD17B10
SCHEMBL2593632 0.76 HPGD (0.41) MAPTHPGDKDM4EALDH1A1HSD17B10
SCHEMBL16892805 0.76 KDM4E (0.42) MAPTHPGDKDM4EALDH1A1HSD17B10
SCHEMBL1819078 0.74 ALDH1A1 (0.43) MAPTHPGDKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230141672-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-05-11 US disclosed
US-9269911-B2 Organic light-emitting device CANON KABUSHIKI KAISHA (JP) 2016-02-23 US disclosed
EP-2564441-A1 ORGANIC LIGHT-EMITTING DEVICE Canon Kabushiki Kaisha (JP) 2013-03-06 EP disclosed
US-20130037791-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2013-02-14 US disclosed
WO-2011136156-A1 ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2011-11-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230141672-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME NECTIN4, SOD1, ELAVL1 MAPT 2415/4885HPGD 4548/4885KDM4E 2176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.