Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.37 |
| ▸ | DBH | P09172 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109040 | 0.79 | GAA (0.50) | CA2ALDH1A1CA1HSD17B10CYP2D6 | |
| SCHEMBL4404010 | 0.77 | GAA (0.46) | GAADRD2DRD4 | |
| SCHEMBL25456032 | 0.77 | GAA (0.46) | GAADRD2DRD4 | |
| SCHEMBL31134655 | 0.75 | MAPT (0.40) | CA2ALDH1A1CA1HSD17B10HSD17B2 | |
| SCHEMBL31621856 | 0.74 | CES1 (0.40) | — | |
| SCHEMBL25471931 | 0.73 | IGF1R (0.47) | CA2CA1HSD17B10TSHRCYP19A1 | |
| SCHEMBL31621854 | 0.70 | TP53 (0.35) | CA2 | |
| SCHEMBL2672815 | 0.70 | MMP1 (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19HDAC8 | |
| SCHEMBL4410681 | 0.70 | MMP1 (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19HDAC8 | |
| SCHEMBL13399537 | 0.69 | MDM2 (0.47) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1540341-A4 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | UNIV ROCHESTER MEDICAL CT (US) | 2007-01-10 | — | — | EP | claimed |
| US-20060166295-A1 | Method for determination of likelihood of occurrence of preterm labor in pregnant females | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-07-27 | — | — | US | claimed |
| EP-1540341-A1 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | The University of Rochester Medical Center (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2004003555-A1 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | UNIVERSITY OF ROCHESTER MEDICAL CENTER (US) | 2004-01-08 | — | — | WO | claimed |
| EP-2299275-B1 | Classification of the oncofetal fibronection level for pregnancy-related indications | ADEZA BIOMEDICAL CORP (US) | 2018-03-07 | — | — | EP | disclosed |
| US-9513298-B2 | Methods for detecting oncofetal fibronectin | BANK OF AMERICA, N.A., AS COLLATERAL AGENT | 2016-12-06 | — | — | US | disclosed |
| US-20150044708-A1 | Methods for Detecting Oncofetal Fibronectin | HOLOGIC, INC. | 2015-02-12 | — | — | US | disclosed |
| US-8852872-B2 | Methods for detecting oncofetal fibronectin | HOLOGIC, INC. (US) | 2014-10-07 | — | — | US | disclosed |
| US-20130171672-A1 | Methods for Detecting Oncofetal Fibronectin | HOLOGIC, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8372581-B2 | Methods for detecting oncofetal fibronectin | CYTYC CORPORATION (US) | 2013-02-12 | — | — | US | disclosed |
| US-20120040356-A1 | Methods for Detecting Oncofetal Fibronectin | CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP | 2012-02-16 | — | — | US | disclosed |
| US-7943294-B2 | Methods for detecting oncofetal fibronectin | HOLOGIC, INC. (US) | 2011-05-17 | — | — | US | disclosed |
| WO-2006026020-A2 | ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN | ADEZA BIOMEDICAL CORPORATION (US) | 2006-03-09 | — | — | WO | disclosed |
| US-20060024724-A1 | Oncofetal fibronectin as a marker for health and disease | CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP | 2006-02-02 | — | — | US | disclosed |
| US-20060024725-A1 | Oncofetal fibronectin as a marker for pregnancy-related indications | THIRD WAVE TECHNOLOGIES, INC. | 2006-02-02 | — | — | US | disclosed |
| US-20060024757-A1 | Detection of oncofetal fibronectin for selection of concepti | CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP | 2006-02-02 | — | — | US | disclosed |
| US-20060024723-A1 | Methods for detecting oncofetal fibronectin | CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP | 2006-02-02 | — | — | US | disclosed |
| US-20060024722-A1 | Samples for detection of oncofetal fibronectin and uses thereof | BIOLUCENT, LLC | 2006-02-02 | — | — | US | disclosed |
| EP-1540341-A1 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | The University of Rochester Medical Center (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004003555-A1 | METHOD FOR DETERMINATION OF LIKELIHOOD OF OCCURRENCE OF PRETERM LABOR IN PREGNANT FEMALES | UNIVERSITY OF ROCHESTER MEDICAL CENTER (US) | 2004-01-08 | — | — | WO | disclosed |