Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704146 | 0.85 | MPI (0.42) | KMT2AMEN1L3MBTL1TDP1MAPT | |
| SCHEMBL2911094 | 0.83 | KMT2A (0.58) | KMT2AMEN1L3MBTL1TDP1HTT | |
| SCHEMBL30791420 | 0.80 | TDP1 (0.47) | KMT2AMEN1L3MBTL1TDP1HTT | |
| SCHEMBL6576087 | 0.80 | TDP1 (0.47) | KMT2AMEN1L3MBTL1TDP1HTT | |
| SCHEMBL8322081 | 0.80 | KMT2A (0.43) | KMT2AMEN1L3MBTL1TDP1HTT | |
| SCHEMBL31415500 | 0.79 | S1PR4 (0.48) | KMT2AMEN1L3MBTL1TDP1HTT | |
| SCHEMBL13140933 | 0.79 | MAPT (0.51) | KMT2AMEN1L3MBTL1TDP1MAPT | |
| SCHEMBL6052357 | 0.79 | SMN1; SMN2 (0.44) | KMT2AMEN1L3MBTL1TDP1HTT | |
| SCHEMBL5857540 | 0.78 | VCAM1 (0.50) | KMT2AMEN1TDP1MAPTALDH1A1 | |
| SCHEMBL31174878 | 0.78 | S1PR4 (0.44) | KMT2AMEN1L3MBTL1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015218-B1 | Amide compounds and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2006-03-21 | — | — | US | disclosed |
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| EP-1176140-A1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2002-01-30 | — | — | EP | disclosed |