Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10157709 | 0.88 | MAPT (0.47) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL4937299 | 0.87 | MAPT (0.46) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL31210319 | 0.86 | MAPT (0.61) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL1929073 | 0.86 | MAPT (0.61) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL10036255 | 0.86 | ALDH1A1 (0.56) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL2780369 | 0.85 | MAPT (0.55) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL282776 | 0.85 | NR1H2 (0.49) | MAPTSMN1; SMN2ALDH1A1KDM4ETP53 | |
| SCHEMBL29649928 | 0.85 | NR1H2 (0.49) | MAPTSMN1; SMN2ALDH1A1KDM4ETP53 | |
| SCHEMBL12581646 | 0.83 | MAPT (0.52) | MAPTSMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL17450416 | 0.83 | ALDH1A1 (0.54) | MAPTSMN1; SMN2GAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015218-B1 | Amide compounds and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2006-03-21 | — | — | US | disclosed |
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| EP-1176140-A1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2002-01-30 | — | — | EP | disclosed |