Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.76 |
| ▸ | LMNA | P02545 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515195 | 0.92 | ALDH1A1 (0.66) | ALDH1A1LMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL5794653 | 0.85 | ALDH1A1 (0.97) | ALDH1A1LMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL7509581 | 0.84 | ALDH1A1 (0.55) | ALDH1A1LMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL5652459 | 0.83 | ALDH1A1 (0.76) | ALDH1A1LMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL3656638 | 0.83 | ALDH1A1 (0.76) | ALDH1A1LMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL2848571 | 0.83 | ALDH1A1 (0.76) | ALDH1A1LMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL853027 | 0.81 | ALDH1A1 (0.72) | ALDH1A1LMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL5652324 | 0.80 | ALDH1A1 (0.67) | ALDH1A1LMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL15321459 | 0.80 | ALDH1A1 (0.71) | ALDH1A1LMNAKMT2ASMN1; SMN2GAA | |
| SCHEMBL25220638 | 0.79 | ALDH1A1 (0.69) | ALDH1A1LMNAKMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7015218-B1 | Amide compounds and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2006-03-21 | — | — | US | disclosed |
| CN-1230421-C | Amide compound and pharmaceutical use thereof | MITSUBISHI CHEM CORP (JP) | 2005-12-07 | — | — | CN | disclosed |
| EP-1176140-B1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| CN-1346348-A | Amide compound and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL (JP) | 2002-04-24 | — | — | CN | disclosed |
| EP-1176140-A1 | AMIDE COMPOUNDS AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2002-01-30 | — | — | EP | disclosed |