Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10315705 | 0.84 | KMT2A (0.46) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL10315707 | 0.84 | KMT2A (0.46) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL20641024 | 0.84 | KMT2A (0.46) | MEN1KMT2AHPGDNPC1RAB9A | |
| SCHEMBL9684904 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2AHPGDLMNAALDH1A1 | |
| SCHEMBL9684900 | 0.83 | ALDH1A1 (0.47) | MEN1KMT2AHPGDLMNAALDH1A1 | |
| SCHEMBL17275362 | 0.81 | KMT2A (0.49) | MEN1KMT2AHPGDTSHRNPC1 | |
| SCHEMBL16932332 | 0.81 | KMT2A (0.49) | MEN1KMT2AHPGDTSHRNPC1 | |
| SCHEMBL28150189 | 0.81 | KMT2A (0.49) | MEN1KMT2AHPGDTSHRNPC1 | |
| SCHEMBL21960658 | 0.80 | TSHR (0.46) | MEN1KMT2AHPGDTSHRLMNA | |
| SCHEMBL5271778 | 0.78 | MEN1 (0.58) | MEN1KMT2AHPGDTSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7034176-B2 | Aminopropylphosphinic acids | ASTRAZENECA AB (SE) | 2006-04-25 | — | — | US | claimed |