SCHEMBL6053337

SCHEMBL6053337

[CH2]CCCn1c(CCC)nc2c(N)nc3cccnc3c21

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.51
TLR8 Q9NR97 3/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10148223 0.87 TLR7 (0.56) TLR7TLR8
SCHEMBL3172977 0.87 TLR7 (0.49) TLR7TLR8
SCHEMBL28765453 0.86 TLR8 (0.53) TLR7TLR8
SCHEMBL4312083 0.85 TLR7 (0.50) TLR7TLR8
SCHEMBL5616992 0.84 TLR7 (0.49) TLR7TLR8
SCHEMBL3352351 0.83 TLR7 (0.73) TLR7TLR8
SCHEMBL5618275 0.83 TLR7 (0.48) TLR7TLR8
SCHEMBL3350352 0.83 TLR7 (0.63) TLR7TLR8
SCHEMBL22359629 0.83 TLR7 (0.54) TLR7TLR8
SCHEMBL5618777 0.82 TLR7 (0.45) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1686992-A2 HYDROXYLAMINE AND OXIME SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES 3M Innovative Properties Company (US) 2006-08-09 EP disclosed
WO-2005051324-A2 HYDROXYLAMINE AND OXIME SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-06-09 WO disclosed