Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4314236 | 0.90 | TLR7 (0.47) | TLR7TLR8 | |
| SCHEMBL13914513 | 0.90 | TLR7 (0.47) | TLR7TLR8 | |
| SCHEMBL4313861 | 0.87 | TLR8 (0.50) | TLR7TLR8 | |
| SCHEMBL4314179 | 0.86 | TLR7 (0.39) | TLR7TLR8 | |
| SCHEMBL6053337 | 0.85 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL5616992 | 0.85 | TLR7 (0.49) | TLR7TLR8 | |
| SCHEMBL10148223 | 0.83 | TLR7 (0.56) | TLR7TLR8 | |
| SCHEMBL3172977 | 0.83 | TLR7 (0.49) | TLR7TLR8 | |
| SCHEMBL3352351 | 0.82 | TLR7 (0.73) | TLR7TLR8 | |
| SCHEMBL5618275 | 0.82 | TLR7 (0.48) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735421-B2 | Imidazoquinolinyl sulfonamides | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-05-27 | — | — | US | disclosed |
| US-20090062272-A1 | IMIDAZOQUINOLINYL SULFONAMIDES | 3M INNOVATIVE PROPERTIES COMPANY | 2009-03-05 | — | — | US | disclosed |
| EP-1699788-A2 | IMIDAZOQUINOLINYL, IMIDAZOPYRIDINYL AND IMIDAZONAPHTHYRIDINYL SULFONAMIDES | 3M Innovative Properties Company (US) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005066169-A2 | IMIDAZOQUINOLINYL, IMIDAZOPYRIDINYL, AND IMIDAZONAPHTHYRIDINYL SULFONAMIDES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062272-A1 | IMIDAZOQUINOLINYL SULFONAMIDES | IL2, EIF2AK2, IFNG | TLR7 167/4885TLR8 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.