Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.94 |
| ▸ | DRD3 | P35462 | 16/20 | 0.94 |
| ▸ | DRD4 | P21917 | 9/20 | 0.93 |
| ▸ | HTR1A | P08908 | 2/20 | 0.83 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.83 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.83 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.83 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14761722 | 0.92 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL14761605 | 0.91 | DRD2 (0.98) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL10950772 | 0.90 | DRD2 (0.98) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL17194866 | 0.90 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL14005958 | 0.89 | DRD2 (0.79) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL14761584 | 0.88 | DRD2 (0.94) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL27978158 | 0.88 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL1156684 | 0.88 | DRD2 (1.00) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL10910646 | 0.88 | DRD2 (0.94) | DRD2DRD3DRD4HTR1AADRA1D | |
| SCHEMBL9653369 | 0.86 | DRD3 (0.72) | DRD2DRD3DRD4HTR1AADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272223-B1 | THERAPEUTIC AND DIAGNOSTIC LIGAND SYSTEMS COMPRISING TRANSPORT MOLECULE BINDING PROPERTIES AND MEDICAMENTS CONTAINING THE SAME | KTB TUMORFORSCHUNGS GMBH (DE) | 2006-05-31 | — | — | EP | disclosed |