Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.31 |
| ▸ | NOS1 | P29475 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19216002 | 0.73 | NOS3 (0.34) | NOS3NOS1NOS2CA1CA2 | |
| SCHEMBL6053599 | 0.71 | — | — | |
| SCHEMBL6053849 | 0.65 | HRH2 (0.31) | NOS3NOS1NOS2CA1CA2 | |
| SCHEMBL6053653 | 0.62 | NOS3 (0.38) | NOS3NOS1NOS2CA1CA2 | |
| SCHEMBL6053649 | 0.62 | NOS3 (0.31) | NOS3NOS1NOS2CA1CA2 | |
| SCHEMBL213703 | 0.61 | — | — | |
| SCHEMBL21344974 | 0.61 | NOS3 (0.31) | NOS3NOS1NOS2CA1CA2 | |
| SCHEMBL4473988 | 0.61 | CA1 (0.30) | CA1CA2CA4 | |
| SCHEMBL6282368 | 0.60 | CYP2A6 (0.32) | — | |
| SCHEMBL20856404 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1629018-A1 | CLASS OF METALLOCENES AND METHOD OF PRODUCING POLYETHYLENE | Univation Technologies LLC (US) | 2006-03-01 | — | — | EP | disclosed |
| US-6911508-B2 | Class of metallocenes and method of producing polyethylene | UNIVATION TECHNOLOGIES, LLC (US) | 2005-06-28 | — | — | US | disclosed |
| WO-2004108771-A1 | CLASS OF METALLOCENES AND METHOD OF PRODUCING POLYETHYLENE | UNIVATION TECHNOLOGIES, LLC (US) | 2004-12-16 | — | — | WO | disclosed |
| US-20040249096-A1 | Class of metallocenes and method of producing polyethylene | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-12-09 | — | — | US | disclosed |