Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204758 | 0.91 | GAA (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27807390 | 0.88 | GAA (0.48) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL1802758 | 0.80 | MGAM (0.41) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL6933557 | 0.79 | MGAM (0.44) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL27485802 | 0.79 | GAA (0.50) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL28080200 | 0.77 | KMT2A (0.36) | TSHRALDH1A1KMT2A | |
| SCHEMBL6053523 | 0.77 | MGAM (0.48) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL1809419 | 0.75 | MGAM (0.37) | MGAMGAASIMGAM2TSHR | |
| Acetone SCHEMBL27953895 | 0.74 | MGAM (0.71) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL1807084 | 0.74 | MGAM (0.35) | MGAMGAASIMGAM2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7022800-B2 | Organosiloxane compositions | DOW CORNING S.A. (BE) | 2006-04-04 | — | — | US | claimed |
| US-20040214965-A1 | Organosiloxane compositions | DOW CORNING S.A. (BE) | 2004-10-28 | — | — | US | claimed |
| EP-1254192-B1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING SA (BE) | 2004-08-04 | — | — | EP | claimed |
| US-7022800-B2 | Organosiloxane compositions | DOW CORNING S.A. (BE) | 2006-04-04 | — | — | US | disclosed |
| US-20040214965-A1 | Organosiloxane compositions | DOW CORNING S.A. (BE) | 2004-10-28 | — | — | US | disclosed |
| EP-1254192-B1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING SA (BE) | 2004-08-04 | — | — | EP | disclosed |