Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8362747 | 0.88 | KCNA3 (0.68) | KCNA3ALDH1A1TAAR1RECQLHTR1B | |
| Ethylene SCHEMBL29058163 | 0.87 | KCNA3 (0.74) | KCNA3ALDH1A1TAAR1RECQLPKM | |
| SCHEMBL27962 | 0.87 | KCNA3 (0.82) | KCNA3ALDH1A1TAAR1RECQLPKM | |
| SCHEMBL5067163 | 0.79 | KCNA3 (0.70) | KCNA3ALDH1A1TAAR1RECQLPKM | |
| SCHEMBL10452423 | 0.79 | KCNA3 (0.70) | KCNA3ALDH1A1TAAR1RECQLPKM | |
| SCHEMBL466750 | 0.79 | KCNA3 (0.70) | KCNA3ALDH1A1TAAR1RECQLPKM | |
| SCHEMBL2481801 | 0.79 | KCNA3 (0.70) | KCNA3ALDH1A1TAAR1RECQLPKM | |
| SCHEMBL11087417 | 0.79 | KCNA3 (0.70) | KCNA3ALDH1A1TAAR1RECQLPKM | |
| SCHEMBL148066 | 0.79 | KCNA3 (0.70) | KCNA3ALDH1A1TAAR1RECQLPKM | |
| SCHEMBL9770391 | 0.79 | KCNA3 (0.70) | KCNA3ALDH1A1TAAR1RECQLPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620945-A | RET inhibitor, pharmaceutical composition thereof and application thereof in medicines | 广东东阳光药业有限公司 | 2021-11-09 | — | — | CN | claimed |
| US-5135932-A | 2-HYDROXYPROPYLAMINO-ALKYL-BENZIMIDAZOLY-5-YL DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEART DISEASE | DR. KARL THOMAE GMBH (DE) | 1992-08-04 | — | — | US | claimed |
| EP-0400519-A1 | 2-Hydroxy-n-propylamines, medicaments containing these compounds and method for preparing them | Dr. Karl Thomae GmbH (DE) | 1990-12-05 | — | — | EP | claimed |
| US-4225706-A | Polychalcogen ester of cephem compound, process for preparing the same and method for removing the protective group of the same | MEIJI SEIKA KAISHA LTD. (JP) | 1980-09-30 | — | — | US | claimed |
| CN-113620945-A | RET inhibitor, pharmaceutical composition thereof and application thereof in medicines | 广东东阳光药业有限公司 | 2021-11-09 | — | — | CN | disclosed |
| US-7122499-B2 | Osmium oxide carried by hydrophilic polymer | Kobayashi, Shu (JP) | 2006-10-17 | — | — | US | disclosed |
| US-20040092779-A1 | Comprising aromatic polyolefin having oxyalkyleneoxyaryl group; solvent and heat resistance; handling | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2004-05-13 | — | — | US | disclosed |
| EP-1366814-A1 | OSMIUM OXIDE DEPOSITED ON HYDROPHILIC POLYMER SUPPORT | Wako Pure Chemical Industries, Ltd. (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-5942522-A | 1-BENZYL-3-ETHOXYCARBONYL-4-DIMETHYLAMINOETHOXY-6-METHYL-2-(1H) -QUINOLINONE; ANTIVIRAL AGAINST DNA CONTAINING VIRUSES, SUCH AS HERPES GROUP VIRUSES | SCHERING CORPORATION (US) | 1999-08-24 | — | — | US | disclosed |
| US-5700938-A | Intermediates for imidazopyridine derivatives | EISAI CO., LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| EP-0549729-B1 | ANTIVIRAL COMPOUNDS AND ANTIHYPERTENSIVE COMPOUNDS | SCHERING CORP (US) | 1997-12-17 | — | — | EP | disclosed |
| US-5618969-A | Intermediates for imidazopyridines | EISAI CO., LTD. (JP) | 1997-04-08 | — | — | US | disclosed |
| US-5175151-A | Useful for treating herpes group viruses | SCHERING CORPORATION (US) | 1992-12-29 | — | — | US | disclosed |
| US-5135932-A | 2-HYDROXYPROPYLAMINO-ALKYL-BENZIMIDAZOLY-5-YL DERIVATIVES AND THEIR USE IN THE TREATMENT OF HEART DISEASE | DR. KARL THOMAE GMBH (DE) | 1992-08-04 | — | — | US | disclosed |
| WO-1992004328-A1 | ANTIVIRAL COMPOUNDS AND ANTIHYPERTENSIVE COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |
| WO-1992004326-A1 | ANTIVIRAL COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |
| WO-1992004327-A1 | ANTIVIRAL COMPOUNDS AND ANTIHYPERTENSIVE COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |
| EP-0400519-A1 | 2-Hydroxy-n-propylamines, medicaments containing these compounds and method for preparing them | Dr. Karl Thomae GmbH (DE) | 1990-12-05 | — | — | EP | disclosed |
| EP-0102324-A2 | Lipids and surfactants in an aqueous medium | CIBA-GEIGY AG (CH) | 1984-03-07 | — | — | EP | disclosed |
| US-4225706-A | Polychalcogen ester of cephem compound, process for preparing the same and method for removing the protective group of the same | MEIJI SEIKA KAISHA LTD. (JP) | 1980-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092779-A1 | Comprising aromatic polyolefin having oxyalkyleneoxyaryl group; solvent and heat resistance; handling | OXER1, OXGR1, AOC2 | KCNA3 1377/4885ALDH1A1 55/4885TAAR1 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.