Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | AHR | P35869 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MGAM | O43451 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12443070 | 1.00 | CYP1A2 (1.00) | CYP1A2POLBKDM4EMAPTGAA | |
| SCHEMBL6635372 | 0.87 | CYP1A2 (0.76) | CYP1A2POLBKDM4EMAPTGAA | |
| SCHEMBL1562661 | 0.87 | CYP1A2 (0.76) | CYP1A2POLBKDM4EMAPTGAA | |
| SCHEMBL1562660 | 0.87 | CYP1A2 (0.76) | CYP1A2POLBKDM4EMAPTGAA | |
| SCHEMBL9369706 | 0.85 | MAPT (0.74) | CYP1A2POLBKDM4EMAPTGAA | |
| SCHEMBL13497036 | 0.85 | MAPT (0.74) | CYP1A2POLBKDM4EMAPTGAA | |
| SCHEMBL8290481 | 0.84 | MAPT (0.76) | CYP1A2POLBMAPTGAAALDH1A1 | |
| SCHEMBL8290446 | 0.84 | CYP1A2 (0.72) | CYP1A2POLBMAPTGAAALDH1A1 | |
| SCHEMBL21258283 | 0.83 | CYP1A2 (0.71) | CYP1A2POLBKDM4EMAPTGAA | |
| SCHEMBL8291227 | 0.83 | TDP1 (0.85) | CYP1A2POLBKDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083199-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2006-08-02 | — | — | EP | claimed |
| EP-1083199-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2006-08-02 | — | — | EP | disclosed |
| US-6506849-B1 | Natural or synthetic rubber; maleimide compound; and polyaniline, hydrazide and/or amine compound; workability, elasticity | BRIDGESTONE CORPORATION (JP) | 2003-01-14 | — | — | US | disclosed |
| EP-1083199-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | BRIDGESTONE CORPORATION (JP) | 2001-03-14 | — | — | EP | disclosed |