Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.76 |
| ▸ | PKM | P14618 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | POLB | P06746 | 5/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.68 |
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 0.68 |
| ▸ | AHR | P35869 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1562661 | 1.00 | CYP1A2 (0.76) | CYP1A2PKMGAAMAPTPOLB | |
| SCHEMBL1562660 | 1.00 | CYP1A2 (0.76) | CYP1A2PKMGAAMAPTPOLB | |
| SCHEMBL28044621 | 0.89 | HTT (0.74) | CYP1A2PKMGAAMAPTPOLB | |
| SCHEMBL8290481 | 0.88 | MAPT (0.76) | CYP1A2PKMGAAMAPTPOLB | |
| SCHEMBL8290446 | 0.88 | CYP1A2 (0.72) | CYP1A2PKMGAAMAPTPOLB | |
| SCHEMBL8291390 | 0.87 | MEN1 (0.81) | CYP1A2PKMGAAMAPTPOLB | |
| SCHEMBL6055366 | 0.87 | CYP1A2 (1.00) | CYP1A2PKMGAAMAPTPOLB | |
| SCHEMBL21258283 | 0.87 | CYP1A2 (0.71) | CYP1A2PKMGAAMAPTPOLB | |
| SCHEMBL12443070 | 0.87 | CYP1A2 (1.00) | CYP1A2PKMGAAMAPTPOLB | |
| SCHEMBL8291227 | 0.87 | TDP1 (0.85) | CYP1A2PKMGAAMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909788-B1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | BRIDGESTONE CORP (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1420044-A2 | Rubber composition and pneumatic tire | Bridgestone Corporation (JP) | 2004-05-19 | — | — | EP | disclosed |
| US-6380288-B1 | LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS | BRIDGESTONE CORPORATION | 2002-04-30 | — | — | US | disclosed |
| EP-0909788-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRES | Bridgestone Corporation (JP) | 1999-04-21 | — | — | EP | disclosed |