Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2966098 | 0.79 | HTR2C (0.35) | ALDH1A1MAPK1 | |
| SCHEMBL2958100 | 0.75 | ALDH1A1 (0.32) | ALDH1A1MAPK1MEN1HPGDALOX15 | |
| SCHEMBL2971252 | 0.70 | KDM1A (0.37) | ALDH1A1MAPK1MEN1HPGDKMT2A | |
| SCHEMBL2964722 | 0.69 | CYP2A6 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2965051 | 0.69 | CYP1A2 (0.32) | ALDH1A1MAPK1HPGDHSD17B10 | |
| SCHEMBL2970663 | 0.69 | CYP1A2 (0.31) | MAPK1 | |
| SCHEMBL2963722 | 0.69 | CYP2A6 (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2958736 | 0.69 | HTR2C (0.34) | ALDH1A1MAPK1 | |
| SCHEMBL2973533 | 0.67 | CA12 (0.33) | ALDH1A1MAPK1 | |
| SCHEMBL2969464 | 0.67 | TACR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006065809-A2 | HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-06-22 | — | — | WO | disclosed |