Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TRPM4 | Q8TD43 | 2/20 | 0.40 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15251759 | 1.00 | DRD2 (0.48) | DRD2DRD1CYP19A1KDM1AMAOA | |
| SCHEMBL3671770 | 1.00 | DRD2 (0.48) | DRD2DRD1CYP19A1KDM1AMAOA | |
| SCHEMBL29607628 | 1.00 | DRD2 (0.48) | DRD2DRD1CYP19A1KDM1AMAOA | |
| SCHEMBL2070340 | 1.00 | DRD2 (0.48) | DRD2DRD1CYP19A1KDM1AMAOA | |
| SCHEMBL15251760 | 1.00 | DRD2 (0.48) | DRD2DRD1CYP19A1KDM1AMAOA | |
| SCHEMBL13084081 | 1.00 | DRD2 (0.48) | DRD2DRD1CYP19A1KDM1AMAOA | |
| SCHEMBL2069258 | 1.00 | DRD2 (0.48) | DRD2DRD1CYP19A1KDM1AMAOA | |
| SCHEMBL3803961 | 1.00 | DRD2 (0.48) | DRD2DRD1CYP19A1KDM1AMAOA | |
| SCHEMBL5620402 | 1.00 | DRD2 (0.48) | DRD2DRD1CYP19A1KDM1AMAOA | |
| SCHEMBL8885782 | 0.95 | DRD2 (0.46) | DRD2DRD1CYP19A1KDM1AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658276-A1 | TRANS-1(6-CHLORO-3-PHENYLINDAN-1-YL)-3,3-DIMETHYLPIPERAZINE | H. Lundbeck A/S (DK) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005016901-A1 | TRANS-1(6-CHLORO-3-PHENYLINDAN-1-YL)-3,3-DIMETHYLPIPERAZINE | H. LUNDBECK A/S (DK) | 2005-02-24 | — | — | WO | disclosed |