Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | IL1RN | P18510 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1319331 | 0.74 | GID4 (0.41) | CYP19A1CYP1A2DRD2DRD1ADRA1A | |
| SCHEMBL12402657 | 0.74 | GID4 (0.41) | CYP19A1CYP1A2DRD2DRD1ADRA1A | |
| SCHEMBL15458494 | 0.74 | GID4 (0.41) | CYP19A1CYP1A2DRD2DRD1ADRA1A | |
| SCHEMBL20478848 | 0.66 | CYP1A2 (0.46) | CYP19A1CYP1A2KDM4EHTR2ADRD2 | |
| SCHEMBL29944710 | 0.65 | — | — | |
| SCHEMBL15262408 | 0.65 | — | — | |
| SCHEMBL15262410 | 0.65 | — | — | |
| SCHEMBL23142120 | 0.64 | MAP3K14 (0.39) | CYP19A1CYP1A2IL1RNERAP2ERAP1 | |
| SCHEMBL2959408 | 0.64 | KDM4E (0.33) | CYP19A1CYP1A2KDM4E | |
| SCHEMBL23142126 | 0.64 | MAP3K14 (0.39) | CYP19A1CYP1A2IL1RNERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006065809-A2 | HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-06-22 | — | — | WO | disclosed |