SCHEMBL6056009

SCHEMBL6056009

CCCCC1=Cc2ccccc2C1Br

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.34
ACHE P22303 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
HTR5A P47898 1/20 0.31
CNR2 P34972 3/20 0.30
CNR1 P21554 1/20 0.30
CYSLTR2 Q9NS75 2/20 0.30
CYSLTR1 Q9Y271 2/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5982091 0.83 HTR2A (0.32)
SCHEMBL5668048 0.82 CYP11B1 (0.32)
SCHEMBL815618 0.81 BCHE (0.35) BCHEACHECYP3A4CYP2D6CYP2C9
SCHEMBL29213166 0.81 BCHE (0.35) BCHEACHECYP3A4CYP2D6CYP2C9
SCHEMBL10644406 0.79 TSHR (0.36) BCHEACHECYP3A4CYP2D6CYP2C9
Fluoride Ion SCHEMBL1131501 0.79 BCHE (0.34) BCHEACHECYP3A4CYP2D6CYP2C9
SCHEMBL18242642 0.79 CYP3A4 (0.36) BCHEACHECYP3A4CYP2D6CYP2C9
SCHEMBL11590486 0.79 BCHE (0.34) BCHEACHECYP3A4CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL813274 0.79 BCHE (0.34) BCHEACHECYP3A4CYP2D6CYP2C9
SCHEMBL29960196 0.78 CYP3A4 (0.33) BCHEACHECYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006065809-A2 HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-06-22 WO disclosed