SCHEMBL29213166

SCHEMBL29213166

[Li]C1C(CCCC)=Cc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.35
ACHE P22303 1/20 0.35
CYP2D6 P10635 3/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
LMNA P02545 2/20 0.34
TDP1 Q9NUW8 1/20 0.32
HTR5A P47898 1/20 0.32
CNR2 P34972 3/20 0.31
CNR1 P21554 1/20 0.31
CYSLTR2 Q9NS75 2/20 0.31
CYSLTR1 Q9Y271 2/20 0.31
KDM4E B2RXH2 1/20 0.30
TP53 P04637 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9860029 0.89 HTR2A (0.32) CYP2D6CYP3A4LMNAKDM4ETP53
SCHEMBL4004558 0.85 HTR2A (0.34) HTR2A
SCHEMBL815618 0.82 BCHE (0.35) BCHEACHECYP2D6CYP3A4CYP2C9
SCHEMBL5859366 0.81 CYP11B1 (0.33) CYP2D6CYP3A4LMNAKDM4ETP53
Fluoride Ion SCHEMBL1131501 0.81 BCHE (0.34) BCHEACHECYP2D6CYP3A4CYP2C9
SCHEMBL10644406 0.81 TSHR (0.36) BCHEACHECYP2D6CYP3A4CYP2C9
SCHEMBL6056009 0.81 BCHE (0.34) BCHEACHECYP2D6CYP3A4CYP2C9
SCHEMBL18242642 0.81 CYP3A4 (0.36) BCHEACHECYP2D6CYP3A4CYP2C9
SCHEMBL11590486 0.81 BCHE (0.34) BCHEACHECYP2D6CYP3A4CYP2C9
Hydrochloric Acid SCHEMBL813274 0.81 BCHE (0.34) BCHEACHECYP2D6CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119080847-A Tetrahydronaphthol-phosphorus monocyclochrome metal complex and preparation method and application thereof 中国石油化工股份有限公司 2024-12-06 CN claimed
CN-118620004-A Phosphine-phenol chromocene metal organic complex, preparation method and application thereof 中国石油化工股份有限公司 2024-09-10 CN claimed
CN-117903217-A Phosphine-phenol single-chromocene metal complex, preparation method and application thereof 中国石油化工股份有限公司 2024-04-19 CN claimed
CN-119080847-A Tetrahydronaphthol-phosphorus monocyclochrome metal complex and preparation method and application thereof 中国石油化工股份有限公司 2024-12-06 CN disclosed
CN-118620004-A Phosphine-phenol chromocene metal organic complex, preparation method and application thereof 中国石油化工股份有限公司 2024-09-10 CN disclosed
CN-117903217-A Phosphine-phenol single-chromocene metal complex, preparation method and application thereof 中国石油化工股份有限公司 2024-04-19 CN disclosed