SCHEMBL6056293

SCHEMBL6056293

C1=C(c2ccccc2)Cc2cccc(-c3ccccc3)c21

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.42
ANPEP P15144 2/20 0.40
IL1RN P18510 1/20 0.40
ERAP2 Q6P179 1/20 0.40
ERAP1 Q9NZ08 1/20 0.40
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
HTR1A P08908 2/20 0.37
HTR7 P34969 2/20 0.37
DPP4 P27487 1/20 0.35
PARP10 Q53GL7 1/20 0.35
PARP11 Q9NR21 1/20 0.35
ALDH1A1 P00352 3/20 0.34
HSD17B10 Q99714 2/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
CYP2A6 P11509 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27988524 0.96 PRCP (0.40) PRCPANPEPIL1RNERAP2ERAP1
SCHEMBL27988523 0.93 PRCP (0.38) PRCPANPEPIL1RNERAP2ERAP1
SCHEMBL29672903 0.92 PRCP (0.39) PRCPANPEPIL1RNERAP2ERAP1
SCHEMBL7172757 0.92 PRCP (0.39) PRCPANPEPIL1RNERAP2ERAP1
Hydrochloric Acid SCHEMBL7175465 0.89 PRCP (0.37) PRCPANPEPIL1RNERAP2ERAP1
Hydrochloric Acid SCHEMBL31539915 0.89 PRCP (0.37) PRCPANPEPIL1RNERAP2ERAP1
SCHEMBL28239564 0.86 PRCP (0.35) PRCPANPEPIL1RNERAP2ERAP1
SCHEMBL30229874 0.81 PDCD1 (0.39) PRCPANPEPIL1RNERAP2ERAP1
SCHEMBL1827132 0.81 PDCD1 (0.39) PRCPANPEPIL1RNERAP2ERAP1
SCHEMBL7730196 0.81 SMARCA2 (0.38) HTR1AHTR7ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107207650-A Conversion method between incompatible catalyst SABIC环球技术有限责任公司 2017-09-26 CN claimed
CN-107207649-A Conversion method between incompatible catalyst SABIC环球技术有限责任公司 2017-09-26 CN claimed
CN-110650965-B Dihydrocarbyl-silyl-bridged-1,3 disubstituted-2-indenyl metallocene complexes for olefin polymerization SABIC环球技术有限责任公司 2022-10-04 CN disclosed
CN-110650965-A Dihydrocarbyl-silyl-bridged-1, 3 disubstituted-2-indenyl metallocene complexes for olefin polymerization SABIC环球技术有限责任公司 2020-01-03 CN disclosed
CN-104981471-B Heterocyclic compound and organic light-emitting element using same 株式会社LG化学 2017-03-08 CN disclosed
US-6995279-B2 Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes CHISSO CORPORATION (JP) 2006-02-07 US disclosed
US-20040127731-A1 Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes CHISSO CORPORATION (JP) 2004-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040127731-A1 Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes MLX, ZYX, YBX1 PRCP 2402/4885ANPEP 4775/4885IL1RN 4675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.