Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | UBE2M | P61081 | 2/20 | 0.45 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6056733 | 0.92 | CCR3 (0.53) | CCR3SLC6A2SLC6A4SLC6A3UBE2M | |
| Trifluoroacetic Acid SCHEMBL6056714 | 0.91 | CCR3 (0.52) | CCR3SLC6A2SLC6A4SLC6A3UBE2M | |
| Trifluoroacetic Acid SCHEMBL6056777 | 0.90 | OPRM1 (0.52) | CCR3SLC6A2SLC6A4MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL6056764 | 0.90 | CCR3 (0.54) | CCR3SLC6A2SLC6A4SLC6A3UBE2M | |
| Trifluoroacetic Acid SCHEMBL6056820 | 0.90 | TSHR (0.56) | CCR3MAPTHSD17B10SLC6A2SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL6056746 | 0.88 | CCR3 (0.49) | CCR3MAPTHSD17B10SLC6A2SLC6A4 | |
| Trifluoroacetic Acid SCHEMBL6056692 | 0.87 | CCR3 (0.49) | CCR3SLC6A2SLC6A4SLC6A3UBE2M | |
| Trifluoroacetic Acid SCHEMBL6056675 | 0.87 | TSHR (0.49) | CCR3MAPTSLC6A2SLC6A4SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL6056731 | 0.86 | USP2 (0.53) | CCR3SLC6A2SLC6A4SLC6A3UBE2M | |
| Trifluoroacetic Acid SCHEMBL6056699 | 0.86 | CCR3 (0.56) | CCR3UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219605-B1 | UREA COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2006-05-10 | — | — | EP | disclosed |
| US-6787650-B1 | CCR5 ANTAGONISTIC ACTIVITY; SUCH AS N-(3-(4-BENZYL-1-PIPERIDINYL)PROPYL)-N'-4-CHLOROPHENYL)-N-PHENYLUREA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2004-09-07 | — | — | US | disclosed |
| EP-1219605-A1 | UREA COMPOUNDS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |