Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448822 | 1.00 | SSTR4 (0.44) | SSTR4 | |
| SCHEMBL4661812 | 0.88 | ALDH1A1 (0.41) | — | |
| SCHEMBL4661814 | 0.88 | ALDH1A1 (0.41) | — | |
| SCHEMBL2636787 | 0.87 | ALDH1A1 (0.42) | SSTR4 | |
| SCHEMBL7441689 | 0.87 | ALDH1A1 (0.42) | SSTR4 | |
| Hydrochloric Acid SCHEMBL7800914 | 0.85 | ALDH1A1 (0.41) | SSTR4 | |
| SCHEMBL7809845 | 0.84 | NPC1 (0.34) | — | |
| SCHEMBL7812352 | 0.84 | MEN1 (0.36) | — | |
| SCHEMBL7800948 | 0.84 | KCNH2 (0.43) | — | |
| SCHEMBL7806075 | 0.83 | HRH1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680113-A2 | DOPAMINE-, NOREPINEPHRINE- AND SEROTONIN- TRANSPORTER- SELECTIVE HETEROCYCLIC COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | GEORGETOWN UNIVERSITY (US) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005041875-A2 | DOPAMINE-, NOREPINEPHRINE- AND SEROTONIN- TRANSPORTER- SELECTIVE HETEROCYCLIC COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | GEORGETOWN UNIVERSITY (US) | 2005-05-12 | — | — | WO | disclosed |