Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 16/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057837 | 0.93 | LCK (0.61) | LCKPKMCISD2HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL6058261 | 0.89 | LCK (0.59) | LCKHSD17B10 | |
| SCHEMBL6057630 | 0.81 | LCK (0.61) | LCKPKM | |
| SCHEMBL6057857 | 0.81 | LCK (0.68) | LCKHSD17B10 | |
| Trifluoroacetic Acid SCHEMBL6058322 | 0.80 | LCK (0.85) | LCKHSD17B10 | |
| SCHEMBL7626156 | 0.79 | PKM (0.53) | LCKPKMCISD2 | |
| SCHEMBL6058131 | 0.78 | LCK (0.66) | LCKPKM | |
| SCHEMBL20554137 | 0.74 | CYP3A4 (0.51) | PKMHSD17B10 | |
| SCHEMBL642545 | 0.73 | CYP3A4 (0.50) | PKMHSD17B10 | |
| SCHEMBL6057883 | 0.71 | LCK (1.00) | LCKHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1037632-B1 | BENZOTHIAZOLE PROTEIN TYROSINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2006-01-11 | — | — | EP | claimed |