SCHEMBL6058428

SCHEMBL6058428

CO/N=C(\CC(=O)OC)c1ccccc1COc1ccccc1C

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
HIF1A Q16665 5/20 0.44
POLB P06746 1/20 0.43
TSHR P16473 1/20 0.43
SGMS2 Q8NHU3 1/20 0.42
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
RXRG P48443 1/20 0.42
TP53 P04637 1/20 0.42
HTT P42858 1/20 0.42
RECQL P46063 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
PTGDR2 Q9Y5Y4 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9822415 0.91 SGMS2 (0.49) MAPTHIF1ASGMS2PTGDR2
SCHEMBL9518002 0.91 SGMS2 (0.49) MAPTHIF1ASGMS2PTGDR2
SCHEMBL28414701 0.90 PTGDR2 (0.46) MAPTTDP1HIF1APOLBTSHR
SCHEMBL12948109 0.86 SGMS2 (0.42) MAPTTDP1POLBTSHRSGMS2
Kresoxim-Methyl SCHEMBL54636 0.82 HIF1A (0.64) MAPTTDP1HIF1ASGMS2RXRA
Kresoxim-Methyl SCHEMBL18664 0.82 HIF1A (0.64) MAPTTDP1HIF1ASGMS2RXRA
Kresoxym-Methyl SCHEMBL12920836 0.82 HIF1A (0.64) MAPTTDP1HIF1ASGMS2RXRA
Kresoxim-Methyl SCHEMBL29356012 0.82 HIF1A (0.64) MAPTTDP1HIF1ASGMS2RXRA
Kresoxim-Methyl SCHEMBL6102704 0.81 HIF1A (0.63) MAPTTDP1HIF1ASGMS2RXRA
SCHEMBL8781729 0.81 HIF1A (0.50) MAPTTDP1HIF1ASGMS2RXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1287739-B1 Water dispersible starch based physical form modification of agricultural agents NAT STARCH CHEM INVEST (US) 2006-05-17 EP disclosed
US-6667277-B2 A solid mixture comprising chemical modified starch, active agricultural material, a surfactant and/or adjuvant; agricultural crop protection; compatible forms, quick release NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION 2003-12-23 US disclosed
US-20030109384-A1 Water dispersible starch based physical form modification of agricultural agents WILMINGTON TRUST (LONDON) LIMITED, AS COLLATERAL AGENT (GB) 2003-06-12 US disclosed
EP-1287739-A1 Water dispersible starch based physical form modification of agricultural agents National Starch and Chemical Investment Holding Corporation (US) 2003-03-05 EP disclosed