⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14668966 | 0.88 | — | — | |
| SCHEMBL6632101 | 0.81 | — | — | |
| SCHEMBL6632920 | 0.81 | — | — | |
| SCHEMBL744196 | 0.81 | SLC6A4 (0.35) | — | |
| SCHEMBL6202386 | 0.77 | — | — | |
| SCHEMBL15934116 | 0.76 | ALOX12 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27092758 | 0.76 | SLC6A4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL21303866 | 0.76 | SLC6A4 (0.31) | — | |
| SCHEMBL6632368 | 0.74 | — | — | |
| SCHEMBL21654282 | 0.74 | SLC6A4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648905-A1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | Abbott Laboratories (US) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005010009-A1 | THIENOPYRIDINE AND FUROPYRIDINE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2005-02-03 | — | — | WO | disclosed |