SCHEMBL6058581

SCHEMBL6058581

[NH]CC([NH])=Cc1ccccc1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.45
TRIM33 Q9UPN9 1/20 0.45
CA2 P00918 8/20 0.44
CA12 O43570 7/20 0.44
KDM4E B2RXH2 2/20 0.44
CA9 Q16790 5/20 0.41
TRPA1 O75762 1/20 0.41
NFKB1 P19838 3/20 0.39
CDK4 P11802 1/20 0.39
CCND1 P24385 1/20 0.39
SIRT2 Q8IXJ6 1/20 0.39
JUN P05412 1/20 0.39
NFE2L2 Q16236 1/20 0.39
CA4 P22748 2/20 0.38
CA1 P00915 1/20 0.38
MAPT P10636 3/20 0.37
LMNA P02545 2/20 0.37
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9640451 0.78 TRIM24 (0.52) TRIM24TRIM33CA2CA12KDM4E
SCHEMBL11535800 0.70 TRIM24 (0.36) TRIM24TRIM33CA2CA12KDM4E
SCHEMBL247861 0.69 TRIM24 (0.52) TRIM24TRIM33CA2CA12KDM4E
SCHEMBL8982379 0.69 TRIM24 (0.52) TRIM24TRIM33CA2CA12KDM4E
SCHEMBL5328884 0.69 TRIM24 (0.52) TRIM24TRIM33CA2CA12KDM4E
SCHEMBL276965 0.69 TRIM24 (0.52) TRIM24TRIM33CA2CA12KDM4E
SCHEMBL10857084 0.69 TRIM24 (0.52) TRIM24TRIM33CA2CA12KDM4E
SCHEMBL2037793 0.69 TRIM24 (0.52) TRIM24TRIM33CA2CA12KDM4E
SCHEMBL31000832 0.69 TRIM24 (0.52) TRIM24TRIM33CA2CA12KDM4E
SCHEMBL30058288 0.68 TRIM24 (0.46) TRIM24TRIM33CA2CA12KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006032465-A1 USE OF STABILIZED THERMOPLASTIC POLYAMIDE MOLDING COMPOUNDS AS A COATING FOR OPTICAL WAVEGUIDES EMS-CHEMIE AG (CH) 2006-03-30 WO disclosed