SCHEMBL276965

SCHEMBL276965

CC(C)=Cc1ccccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.52
TRIM33 Q9UPN9 1/20 0.52
LMNA P02545 2/20 0.52
MAPT P10636 2/20 0.52
TRPA1 O75762 1/20 0.46
CA2 P00918 8/20 0.45
CA12 O43570 7/20 0.45
CA9 Q16790 5/20 0.45
NFKB1 P19838 3/20 0.45
KDM4E B2RXH2 2/20 0.45
CDK4 P11802 1/20 0.45
CCND1 P24385 1/20 0.45
SIRT2 Q8IXJ6 1/20 0.45
JUN P05412 1/20 0.45
NFE2L2 Q16236 1/20 0.45
RAB9A P51151 2/20 0.44
CA4 P22748 2/20 0.43
CA1 P00915 1/20 0.43
NPC1 O15118 1/20 0.43
GMNN O75496 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31000832 1.00 TRIM24 (0.52) TRIM24TRIM33LMNAMAPTTRPA1
SCHEMBL2340381 0.84 LMNA (0.38) TRIM24TRIM33LMNAMAPTTRPA1
SCHEMBL4954904 0.83 LMNA (0.43) TRIM24TRIM33LMNAMAPTTRPA1
SCHEMBL12957563 0.81 MAPT (0.48) TRIM24TRIM33LMNAMAPTTRPA1
SCHEMBL9618491 0.81 ERN1 (0.61) LMNAMAPTTRPA1CA2KDM4E
SCHEMBL28409034 0.79 MAPT (0.47) TRIM24TRIM33LMNAMAPTTRPA1
SCHEMBL7113862 0.79 ERN1 (0.43) TRIM24TRIM33LMNAMAPTTRPA1
SCHEMBL5992999 0.79 TRPA1 (0.48) TRIM24TRIM33LMNAMAPTTRPA1
SCHEMBL16307959 0.78 APP (0.40) TRIM24TRIM33LMNAMAPTTRPA1
SCHEMBL2359891 0.78 ERN1 (0.42) TRIM24TRIM33LMNAMAPTTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 386 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3697873-B1 METHOD FOR REDUCING LOW SPEED PRE-IGNITION SHELL INT RESEARCH (NL) 2021-05-26 EP claimed
US-20200283691-A1 METHOD FOR REDUCING LOW SPEED PRE-IGNITION SHELL OIL COMPANY 2020-09-10 US claimed
EP-3697873-A1 METHOD FOR REDUCING LOW SPEED PRE-IGNITION Shell Internationale Research Maatschappij B.V. (NL) 2020-08-26 EP claimed
CN-111212891-A Method for reducing low speed pre-ignition 国际壳牌研究有限公司 2020-05-29 CN claimed
CN-106103667-B Mixed detergent composition for intake valve deposit control 雅富顿化学公司 2019-12-10 CN claimed
US-10457884-B2 Mixed detergent composition for intake valve deposit control AFTON CHEMICAL CORPORATION (US) 2019-10-29 US claimed
WO-2019079246-A1 METHOD FOR REDUCING LOW SPEED PRE-IGNITION SHELL OIL COMPANY (US) 2019-04-25 WO claimed
CN-106085649-B A kind of carb cleaner and preparation method thereof 广州保赐利化工有限公司 2018-10-02 CN claimed
CN-106010825-B A kind of carb cleaner and preparation method thereof 广州保赐利化工有限公司 2018-05-01 CN claimed
EP-1226188-B2 METHOD FOR PRODUCING MANNICH ADDUCTS THAT CONTAIN POLYISOBUTYLENE PHENOL BASF SE (DE) 2017-11-22 EP claimed
WO-2006105025-A1 SOLID ADDITIVE COMPOSITION AND METHOD THEREOF THE LUBRIZOL CORPORATION (US) 2006-10-05 WO claimed
EP-1385928-B1 METHOD FOR PURIFYING LONG-CHAIN ALKYL PHENOLS AND THE MANNICH ADDUCTS THEREOF BASF AG (DE) 2006-01-25 EP claimed
US-20050171294-A1 Used as detergent additives in fuel BASF AKTIENGESELLSCHAFT (DE) 2005-08-04 US claimed
US-6914163-B2 Method for producing polyisobutylphenols BASF AG (DE) 2005-07-05 US claimed
US-6875897-B1 Method for producing polyisobutenylphenols BASF AKTIENGESELLSCHAFT (DE) 2005-04-05 US claimed
EP-1320556-B1 METHOD FOR PRODUCING POLYISOBUTENYLPHENOLES BASF AG (DE) 2004-12-08 EP claimed
EP-1226188-B1 METHOD FOR PRODUCING MANNICH ADDUCTS THAT CONTAIN POLYISOBUTYLENE PHENOL BASF AG (DE) 2004-12-01 EP claimed
EP-1233990-B1 METHOD FOR PRODUCING MANNICH ADDUCTS THAT CONTAIN POLYISOBUTYLENE PHENOL BASF AG (DE) 2004-02-18 EP claimed
US-20030187171-A1 Method for producing polyisobutylphenols BASF AKTIENGESELLSCHAFT (DE) 2003-10-02 US claimed
US-4767551-A OVERBASED COPPER CONTAINING COMPOUND AMOCO CORPORATION (US) 1988-08-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030187171-A1 Method for producing polyisobutylphenols PCNA, PCBP1, PAH TRIM24 824/4885TRIM33 153/4885LMNA 1476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.