Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6059326 | 0.86 | GPR119 (0.48) | GPR119EPHX1MMP13DPP4HPGD | |
| SCHEMBL2673897 | 0.85 | GPR119 (0.47) | GPR119EPHX1MMP13DPP4HPGD | |
| SCHEMBL6058985 | 0.80 | GPR119 (0.48) | GPR119EPHX1DPP4HPGDNPC1 | |
| SCHEMBL25819368 | 0.78 | GPR119 (0.56) | GPR119EPHX1DPP4HPGDNPC1 | |
| SCHEMBL25819386 | 0.78 | GPR119 (0.56) | GPR119EPHX1DPP4HPGDNPC1 | |
| SCHEMBL13600068 | 0.78 | GPR119 (0.56) | GPR119EPHX1DPP4HPGDNPC1 | |
| SCHEMBL3420058 | 0.77 | NR1H2 (0.41) | GPR119MMP13DPP4 | |
| SCHEMBL20232931 | 0.76 | EPHX1 (0.54) | GPR119EPHX1DPP4HPGDNPC1 | |
| SCHEMBL21995290 | 0.75 | HPGD (0.49) | GPR119EPHX1MMP13DPP4HPGD | |
| SCHEMBL4429810 | 0.75 | HPGD (0.49) | GPR119EPHX1MMP13DPP4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071175-B1 | Pyridine mercapto carboxylic acids as carboxypeptidase U inhibitors | ASTRAZENECA AB (SE) | 2006-07-04 | — | — | US | disclosed |