Maleic Anhydride

Maleic Anhydride

SCHEMBL6059149

O=C1C=CC(=O)O1.OB(O)O

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Anhydride SCHEMBL28180718 0.86 ALDH1A1 (0.34) HSP90AA1ALDH1A1CYP2C9HPGDALOX15
Maleic Anhydride SCHEMBL1761076 0.86 ALDH1A1 (0.37) HSP90AA1ALDH1A1CYP2C9HPGDALOX15
Maleic Anhydride SCHEMBL10482080 0.86 ALDH1A1 (0.37) HSP90AA1ALDH1A1CYP2C9HPGDALOX15
SCHEMBL10426127 0.86 ALDH1A1 (0.37) HSP90AA1ALDH1A1CYP2C9HPGDALOX15
Maleic Anhydride SCHEMBL191 0.86
Maleic Anhydride SCHEMBL10482026 0.86 ALDH1A1 (0.37) HSP90AA1ALDH1A1CYP2C9HPGDALOX15
Maleic Anhydride SCHEMBL1332547 0.86
Maleic Anhydride SCHEMBL1332543 0.86
Maleic Anhydride SCHEMBL28740916 0.83
Maleic Anhydride SCHEMBL193675 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1299427-B1 PROCESS FOR PREPARING ANHYDRIDE-GRAFTED POLYMERS WITH IMPROVED COLOUR DU PONT (US) 2006-08-30 EP disclosed
EP-1299427-A1 PROCESS FOR PREPARING ANHYDRIDE-GRAFTED POLYMERS WITH IMPROVED COLOUR DUPONT CANADA INC. (CA) 2003-04-09 EP disclosed
US-6380320-B1 GRAFTING A POLYOLEFIN WITH AN ANHYDRIDE IN PRESENCE OD OXOBORON COMPOUND DUPONT CANADA INC. (CA) 2002-04-30 US disclosed
WO-2002032970-A1 PROCESS FOR PREPARING ANHYDRIDE-GRAFTED POLYMERS WITH IMPROVED COLOUR DUPONT CANADA INC. (CA) 2002-04-25 WO disclosed