Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4198066 | 0.88 | TSHR (0.67) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL27574139 | 0.85 | TSHR (0.58) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4619099 | 0.85 | TSHR (0.70) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL27617315 | 0.82 | TSHR (0.76) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Acrylamide SCHEMBL10979100 | 0.82 | TSHR (0.66) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Acrylic Acid Ethyl Ester SCHEMBL28065112 | 0.81 | TDP1 (0.48) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| Urethane SCHEMBL9064785 | 0.81 | ALOX15 (0.60) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7516575 | 0.81 | TSHR (0.44) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL27957904 | 0.81 | TSHR (0.68) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4873976 | 0.80 | TSHR (0.75) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132476-B2 | Thermosetting compositions containing alternating copolymers of isobutylene type monomers | PPG INDUSTRIES OHIO, INC. (US) | 2006-11-07 | — | — | US | disclosed |
| US-20040242777-A1 | Thermosetting compositions containing alternating copolymers of isobutylene type monomers | COCA SIMION (US) | 2004-12-02 | — | — | US | disclosed |