SCHEMBL6060503

SCHEMBL6060503

CCCCCCC1(C(=O)O)CCCC1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.46
PTPN1 P18031 3/20 0.36
ACP1 P24666 1/20 0.36
CDC25B P30305 1/20 0.36
GPR84 Q9NQS5 5/20 0.33
PPARG P37231 5/20 0.33
PPARD Q03181 5/20 0.33
PPARA Q07869 5/20 0.33
HDAC11 Q96DB2 4/20 0.33
TSHR P16473 3/20 0.33
PRKCA P17252 3/20 0.33
ALDH1A1 P00352 2/20 0.33
TLR2 O60603 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
MEN1 O00255 2/20 0.33
FABP4 P15090 2/20 0.33
KMT2A Q03164 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
SLC22A8 Q8TCC7 1/20 0.33
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060384 1.00 SIRT2 (0.46) SIRT2PTPN1ACP1CDC25BGPR84
SCHEMBL6060679 0.93 SIRT2 (0.38) SIRT2PTPN1ACP1CDC25BMEN1
SCHEMBL6060737 0.86 SIRT2 (0.33) SIRT2TSHRMEN1KMT2A
SCHEMBL11620033 0.84 CYP2C19 (0.31)
SCHEMBL4812034 0.83 SIRT2 (0.43) SIRT2
SCHEMBL6905227 0.83 SIRT2 (0.43) SIRT2
SCHEMBL28553004 0.83 SIRT2 (0.43) SIRT2PRKCA
SCHEMBL1044076 0.82
SCHEMBL1044757 0.81 CYP4F2 (0.30)
SCHEMBL1082424 0.81 CETP (0.33) TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006045246-A1 CYCLOPENTANE CARBOXYLATE COMPOUNDS, PROCESS AND INTERMEDIATES FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-05-04 WO disclosed