SCHEMBL6060679

SCHEMBL6060679

CCCCC1(C(=O)O)CCCC1=O

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 1/20 0.38
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PTPN1 P18031 1/20 0.32
ACP1 P24666 1/20 0.32
CDC25B P30305 1/20 0.32
CETP P11597 2/20 0.31
POLB P06746 1/20 0.31
HSD17B10 Q99714 1/20 0.30
CYP19A1 P11511 4/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060384 0.93 SIRT2 (0.46) SIRT2MEN1KMT2APTPN1ACP1
SCHEMBL6060503 0.93 SIRT2 (0.46) SIRT2MEN1KMT2APTPN1ACP1
SCHEMBL6060737 0.89 SIRT2 (0.33) SIRT2MEN1KMT2APOLB
SCHEMBL1044757 0.84 CYP4F2 (0.30)
SCHEMBL1082424 0.84 CETP (0.33) MEN1KMT2ACETPPOLBCNR2
SCHEMBL11620033 0.84 CYP2C19 (0.31)
SCHEMBL1043200 0.83
SCHEMBL1749522 0.82 CYP3A4 (0.32)
SCHEMBL1044076 0.81
SCHEMBL4804036 0.81 CYP2C19 (0.39) SIRT2MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006045246-A1 CYCLOPENTANE CARBOXYLATE COMPOUNDS, PROCESS AND INTERMEDIATES FOR PREPARING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-05-04 WO disclosed