Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14174134 | 0.83 | PDK2 (0.45) | APEX1ELANEPDK2CYP3A4TSHR | |
| SCHEMBL19704581 | 0.82 | PDK2 (0.39) | APEX1ELANEPDK2KCNQ2 | |
| SCHEMBL19718513 | 0.82 | PDK2 (0.36) | APEX1ELANEPDK2 | |
| SCHEMBL17358869 | 0.79 | PDK2 (0.40) | APEX1ELANEPDK2CYP1A2CYP3A4 | |
| SCHEMBL24314140 | 0.78 | PDK2 (0.38) | APEX1ELANEPDK2RAB9ATHRB | |
| SCHEMBL3782236 | 0.78 | APEX1 (0.48) | APEX1PDK2KCNQ2CYP1A2CYP3A4 | |
| SCHEMBL29441927 | 0.77 | APEX1 (0.51) | APEX1PDK2CYP1A2TSHRTHRB | |
| SCHEMBL21219235 | 0.77 | APEX1 (0.51) | APEX1PDK2CYP1A2TSHRTHRB | |
| SCHEMBL6705752 | 0.77 | APEX1 (0.36) | APEX1PDK2KCNQ2CYP1A2CYP3A4 | |
| SCHEMBL15691676 | 0.75 | APEX1 (0.46) | APEX1PDK2RAB9ATHRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103864586-B | Bis ether compound and resin combination with fluorene skeleton | 新日铁住金化学株式会社 | 2018-01-09 | — | — | CN | disclosed |
| EP-1298117-B1 | Method for preparing bromofluorenes | JFE CHEMICAL CORP (JP) | 2006-02-15 | — | — | EP | disclosed |
| US-6858764-B2 | Method for preparing bromofluorenes | JFE CHEMICAL CORPORATION (JP) | 2005-02-22 | — | — | US | disclosed |
| US-20030065226-A1 | Method for preparing bromofluorenes | ADCHEMCO CORPORATION (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1298117-A2 | Method for preparing bromofluorenes | Adchemco Corporation (JP) | 2003-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065226-A1 | Method for preparing bromofluorenes | FLNB, AFF2, BRPF1 | APEX1 1019/4885ELANE 1360/4885PDK2 2076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.