Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 3/20 | 0.56 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PRKCA | P17252 | 6/20 | 0.54 |
| ▸ | RASGRP3 | Q8IV61 | 5/20 | 0.54 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.54 |
| ▸ | CLK1 | P49759 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051164 | 0.81 | KMT2A (0.62) | MAPTCYP1A2 | |
| SCHEMBL3076077 | 0.74 | KMT2A (0.65) | DYRK1ADYRK1BMAPTCLK1 | |
| SCHEMBL27260229 | 0.72 | DYRK1A (1.00) | DYRK1ADYRK1BMAPTCLK1CYP1A2 | |
| SCHEMBL9049784 | 0.72 | DYRK1A (0.59) | DYRK1ADYRK1BMAPTCLK1CYP1A2 | |
| SCHEMBL9566863 | 0.72 | DYRK1A (1.00) | DYRK1ADYRK1BMAPTCLK1CYP1A2 | |
| SCHEMBL9049778 | 0.72 | DYRK1A (0.59) | DYRK1ADYRK1BMAPTCLK1CYP1A2 | |
| SCHEMBL23633280 | 0.72 | CYP1A2 (0.86) | DYRK1ADYRK1BMAPTCLK1CYP1A2 | |
| SCHEMBL17693071 | 0.72 | CYP1A2 (0.86) | DYRK1ADYRK1BMAPTCLK1CYP1A2 | |
| SCHEMBL28494165 | 0.71 | DYRK1A (0.57) | DYRK1ADYRK1BMAPTCLK1CYP1A2 | |
| SCHEMBL6059814 | 0.70 | DYRK1A (1.00) | DYRK1ADYRK1BMAPTCLK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008593-B1 | Benzylidene-gamma-butyrolactones, process for their production and use thereof as UV absorbers | SYMRISE GMBH & CO KG (DE) | 2006-05-10 | — | — | EP | disclosed |
| US-6258963-B1 | DRUGS, COSMETICS | HAARMANN & REIMER GMBH (DE) | 2001-07-10 | — | — | US | disclosed |
| EP-1008593-A1 | Benzylidene-gamma-butyrolactones, process for their production and use thereof as UV absorbers | HAARMANN & REIMER GMBH (DE) | 2000-06-14 | — | — | EP | disclosed |