Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.86 |
| ▸ | EGFR | P00533 | 6/20 | 0.73 |
| ▸ | XDH | P47989 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.63 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.63 |
| ▸ | MIF | P14174 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.62 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.62 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17693071 | 1.00 | CYP1A2 (0.86) | CYP1A2EGFRXDHMAPTDYRK1A | |
| SCHEMBL17693074 | 0.93 | CYP1A2 (1.00) | CYP1A2EGFRXDHMAPTDYRK1A | |
| SCHEMBL17077381 | 0.92 | EGFR (0.88) | CYP1A2EGFRXDHNFE2L2 | |
| SCHEMBL17077379 | 0.92 | EGFR (0.88) | CYP1A2EGFRXDHNFE2L2 | |
| SCHEMBL1524473 | 0.88 | CYP1A2 (0.69) | CYP1A2EGFRXDHMAPTDYRK1A | |
| SCHEMBL1524472 | 0.88 | CYP1A2 (0.69) | CYP1A2EGFRXDHMAPTDYRK1A | |
| SCHEMBL17691416 | 0.87 | CYP1A2 (0.68) | CYP1A2EGFRXDHMAPTDYRK1A | |
| SCHEMBL18513420 | 0.87 | CYP1A2 (0.88) | CYP1A2EGFRXDHMAPTDYRK1A | |
| SCHEMBL15940309 | 0.85 | CYP1A2 (0.69) | CYP1A2EGFRXDHMAPTDYRK1A | |
| SCHEMBL15940308 | 0.85 | CYP1A2 (0.69) | CYP1A2EGFRXDHMAPTDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309617-A1 | INHIBITION OF RESPIRATORY COMPLEX III BY LIGANDS THAT INTERACT WITH A REGULATORY SWITCH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-07 | — | — | US | disclosed |
| US-11058645-B2 | Inhibition of respiratory complex III by ligands that interact with a regulatory switch | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309617-A1 | INHIBITION OF RESPIRATORY COMPLEX III BY LIGANDS THAT INTERACT WITH A REGULATORY SWITCH | MT-CO3, NDUFV3, MT-ND3 | CYP1A2 2181/4885EGFR 2876/4885XDH 709/4885 |
| US-11058645-B2 | Inhibition of respiratory complex III by ligands that interact with a regulatory switch | MT-CO3, NDUFV3, MT-ND3 | CYP1A2 2181/4885EGFR 2876/4885XDH 709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.