Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.44 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788835 | 0.97 | ABL1 (0.49) | ALDH1A1MAPTKDM4EGAAABL1 | |
| SCHEMBL13911196 | 0.88 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EGAAMAPK1 | |
| SCHEMBL23174566 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EGAAMAPK1 | |
| SCHEMBL11935019 | 0.82 | STK17A (0.51) | ALDH1A1MAPTKDM4EGAAPOLB | |
| SCHEMBL1931259 | 0.81 | ABL1 (0.50) | ALDH1A1MAPTABL1POLBKMT2A | |
| SCHEMBL7212426 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EGAAPOLB | |
| SCHEMBL9068819 | 0.79 | ABL1 (0.43) | ALDH1A1MAPTKDM4EGAAABL1 | |
| SCHEMBL355896 | 0.78 | NPC1 (0.44) | ALDH1A1MAPTKDM4EGAAPOLB | |
| SCHEMBL11941006 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EGAAABL1 | |
| SCHEMBL11940784 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTKDM4EGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1680447-A2 | ORTHOGONAL GENE SWITCHES | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-07-19 | — | — | EP | disclosed |
| WO-2005040212-A2 | ORTHOGONAL GENE SWITCHES | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2005-05-06 | — | — | WO | disclosed |