Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818094 | 0.92 | CYP3A4 (0.36) | CYP3A4CYP2C9L3MBTL1GAA | |
| SCHEMBL1814419 | 0.90 | CYP3A4 (0.35) | CYP3A4CYP2C9OPRM1OPRL1 | |
| SCHEMBL1814676 | 0.81 | CYP3A4 (0.46) | CYP3A4CYP2C9 | |
| SCHEMBL1816294 | 0.80 | CYP3A4 (0.35) | CYP3A4CYP2C9L3MBTL1GBA1GAA | |
| SCHEMBL4885373 | 0.76 | CYP3A4 (0.36) | CYP3A4CYP2C9 | |
| SCHEMBL4887936 | 0.76 | CYP3A4 (0.34) | CYP3A4CYP2C9 | |
| SCHEMBL5634862 | 0.69 | CYP3A4 (0.41) | CYP3A4CYP2C9KMT2A | |
| SCHEMBL5634281 | 0.69 | CYP3A4 (0.41) | CYP3A4CYP2C9LMNAL3MBTL1GAA | |
| SCHEMBL10921468 | 0.65 | ATP4A (0.51) | CYP3A4CYP2C9 | |
| SCHEMBL7142034 | 0.65 | CYP3A4 (0.38) | CYP3A4CYP2C9GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663313-A2 | COMPOSITIONS USEFUL FOR TREATING GASTROINTESTINAL MOTILITY DISORDERS | Dynogen Pharmaceuticals Inc. (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005021040-A2 | COMPOSITIONS USEFUL FOR TREATING GASTROINTESTINAL MOTILITY DISORDERS | DYNOGEN PHARMACEUTICALS, INC. (US) | 2005-03-10 | — | — | WO | disclosed |