Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PMM2 | O15305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3179411 | 1.00 | HSP90AA1 (0.53) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL13480838 | 1.00 | HSP90AA1 (0.53) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL7172086 | 1.00 | HSP90AA1 (0.53) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL3179405 | 1.00 | HSP90AA1 (0.53) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL13889804 | 0.88 | HSP90AA1 (0.47) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL3183709 | 0.83 | ATM (0.66) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL13870646 | 0.83 | ATM (0.66) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL13480904 | 0.83 | ATM (0.66) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL3183696 | 0.83 | ATM (0.66) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL3180518 | 0.81 | L3MBTL1 (0.52) | HSP90AA1SLC6A2SLC6A4SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141578-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-11-28 | — | — | US | disclosed |