Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5545362 | 0.89 | CNR2 (0.41) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5545559 | 0.89 | L3MBTL1 (0.41) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5540640 | 0.88 | MEN1 (0.48) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5538946 | 0.87 | L3MBTL1 (0.41) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5545369 | 0.87 | L3MBTL1 (0.40) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5543127 | 0.86 | L3MBTL1 (0.41) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5539155 | 0.85 | EGLN1 (0.40) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5539051 | 0.85 | CNR2 (0.42) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5545367 | 0.84 | CNR2 (0.42) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL5545774 | 0.84 | CNR2 (0.42) | MEN1KMT2AL3MBTL1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720856-A2 | HIV INTEGRASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005077050-A2 | HIV INTEGRASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-08-25 | — | — | WO | disclosed |