Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606228 | 1.00 | NPC1 (0.50) | NPC1RAB9AKMT2APOLBTDP1 | |
| SCHEMBL17681456 | 0.90 | NPC1 (0.42) | NPC1RAB9AKMT2APOLBTDP1 | |
| SCHEMBL17681420 | 0.90 | POLB (0.44) | NPC1RAB9AKMT2APOLBTDP1 | |
| SCHEMBL17681421 | 0.90 | POLB (0.44) | NPC1RAB9AKMT2APOLBTDP1 | |
| SCHEMBL17681457 | 0.90 | NPC1 (0.42) | NPC1RAB9AKMT2APOLBTDP1 | |
| SCHEMBL599733 | 0.89 | ALDH1A1 (0.45) | KMT2APPARGPPARACYP2C9CYP2C19 | |
| SCHEMBL598817 | 0.88 | SCN2A (0.43) | NPC1RAB9AKMT2APPARGPPARA | |
| SCHEMBL598818 | 0.88 | SCN2A (0.43) | NPC1RAB9AKMT2APPARGPPARA | |
| SCHEMBL17681404 | 0.86 | CMA1 (0.45) | KMT2APPARGPPARACYP2C9CYP2C19 | |
| SCHEMBL17681405 | 0.86 | CMA1 (0.45) | KMT2APPARGPPARACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315442-B2 | Method for manufacturing optically active carboxylic acid ester | TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2016-04-19 | — | — | US | disclosed |
| US-8115008-B2 | Method for producing optically active ester and method for producing optically active carboxylic acid | TOKYO UNIVERSITY OF SCIENCE EDUCATION FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) | 2012-02-14 | — | — | US | disclosed |